BDBM6792 7,18-dimethyl-3,13,18-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4(9),5,7,11(15),17(21),19,22-nonaene-12,14-dione::indolo[6,7-a]pyrrolo[3,4-c]carbazole deriv. 3k

SMILES Cc1ccc2[nH]c3c(c4C(=O)NC(=O)c4c4c5n(C)ccc5ccc34)c2c1

InChI Key InChIKey=UVFCCXBRHTYMDK-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 6792   

LigandPNGBDBM6792(7,18-dimethyl-3,13,18-triazahexacyclo[14.7.0.0^{2,...)
Affinity DataIC50: 393nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2005
Entry Details Article
PubMed
LigandPNGBDBM6792(7,18-dimethyl-3,13,18-triazahexacyclo[14.7.0.0^{2,...)
Affinity DataIC50: 407nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2005
Entry Details Article
PubMed
LigandPNGBDBM6792(7,18-dimethyl-3,13,18-triazahexacyclo[14.7.0.0^{2,...)
Affinity DataIC50: 1.07E+3nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2005
Entry Details Article
PubMed
LigandPNGBDBM6792(7,18-dimethyl-3,13,18-triazahexacyclo[14.7.0.0^{2,...)
Affinity DataIC50: 4.06E+3nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2005
Entry Details Article
PubMed
LigandPNGBDBM6792(7,18-dimethyl-3,13,18-triazahexacyclo[14.7.0.0^{2,...)
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2017
Entry Details Article
PubMed