BDBM681761 Synthesis of N-((2′-(3,5-difluoro-2,6-dimethoxypyridine-4-yl)-3′-oxo-2′,3′-dihydro-1′H-spiro[cyclopropane-1,4′-[2,7]naphthine]-6′-yl) methyl) acrylamide ::US20240199625, Compound 1

SMILES COc1nc(OC)c(F)c(N2Cc3cnc(CNC(=O)C=C)cc3C3(CC3)C2=O)c1F

InChI Key InChIKey=WVVDRTQPKRPGAK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 681761   

TargetFibroblast growth factor receptor 1(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM681761(US20240199625, Compound 1 | Synthesis of N-((2R...)
Affinity DataIC50: 3.66E+3nMAssay Description:Compound preparation: Add 45 μL of DMSO to 5 μL of stock solution at a concentration of 10 mM to prepare the solution LY2874455 at 1000 M; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2024
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 4(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM681761(US20240199625, Compound 1 | Synthesis of N-((2R...)
Affinity DataIC50: 8.57nMAssay Description:Compound preparation: Add 45 μL of DMSO to 5 μL of stock solution at a concentration of 10 mM to prepare the solution LY2874455 at 1000 M; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2024
Entry Details
Go to US Patent