BDBM682034 US20240207238, Example 4

SMILES Fc1cc(CNc2cc(ccn2)C2CC2)c2cn[nH]c2c1N1CC(=O)NS1(=O)=O

InChI Key InChIKey=PEAPOPMVEAPZCW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 682034   

TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM682034(US20240207238, Example 4)
Affinity DataIC50: 1nMAssay Description:A PhosphoSens kinase assay was performed as described by the vendor (AssayQuant Technologies, Marlborough, MA). Briefly, 1000x solutions of compounds...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
Go to US Patent

TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM682034(US20240207238, Example 4)
Affinity DataIC50: 2nMAssay Description:The PTPN2 biochemical assay was performed as follows, a 5× stock solution of human PTPN2 (SRP5075, MilliporeSigma, Burlington, MA) and a 1.25× stock ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
Go to US Patent