BDBM6821 3-(2-hydroxyethyl)-6-methoxy-18-methyl-3,13,18-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4(9),5,7,11(15),17(21),19,22-nonaene-12,14-dione::indolo[6,7-a]pyrrolo[3,4-c]carbazole deriv. 3nn

SMILES COc1ccc2c(c1)n(CCO)c1c2c2C(=O)NC(=O)c2c2c3n(C)ccc3ccc12

InChI Key InChIKey=NYEAMHXTSOXUPE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 6821   

LigandPNGBDBM6821(3-(2-hydroxyethyl)-6-methoxy-18-methyl-3,13,18-tri...)
Affinity DataIC50: 24nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2005
Entry Details Article
PubMed
LigandPNGBDBM6821(3-(2-hydroxyethyl)-6-methoxy-18-methyl-3,13,18-tri...)
Affinity DataIC50: 47nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2005
Entry Details Article
PubMed
LigandPNGBDBM6821(3-(2-hydroxyethyl)-6-methoxy-18-methyl-3,13,18-tri...)
Affinity DataIC50: 101nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2005
Entry Details Article
PubMed
LigandPNGBDBM6821(3-(2-hydroxyethyl)-6-methoxy-18-methyl-3,13,18-tri...)
Affinity DataIC50: 1.62E+3nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2005
Entry Details Article
PubMed