BDBM682814 2-cyclobutyl-7-(5-fluoropyridin- 3-yl)-5,7- diazaspiro[3.4]octane-6,8- dione::US20240208970, Compound 13

SMILES Fc1cncc(c1)N1C(=O)NC2(CC(C2)C2CCC2)C1=O

InChI Key InChIKey=FOZLXSUKKDDCIZ-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 682814   

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandPNGBDBM682814(US20240208970, Compound 13 | 2-cyclobutyl-7-(5-flu...)
Affinity DataIC50: 6.70E+3nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandPNGBDBM682814(US20240208970, Compound 13 | 2-cyclobutyl-7-(5-flu...)
Affinity DataKd:  6.60E+4nMAssay Description:The SPR experiments were performed using a Biacore S200 instrument and CM5 biosensor chips (Cytiva, Uppsala, Sweden) at 25 C. Streptavidin (Sigma) wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
Go to US Patent