BDBM682837 2-(3-bromothiophen-2- yl)-7-(isoquinolin-4-yl)- 5,7- diazaspiro[3.4]octane- 6,8-dione::US20240208970, Compound 44::US20240208970, Compound 45

SMILES Brc1ccsc1C1CC2(C1)NC(=O)N(C2=O)c1cncc2ccccc12

InChI Key InChIKey=MOXCGRCJBAULFS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 682837   

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandPNGBDBM682837(US20240208970, Compound 44 | US20240208970, Compou...)
Affinity DataIC50: 81nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandPNGBDBM682837(US20240208970, Compound 44 | US20240208970, Compou...)
Affinity DataIC50: 57nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
Go to US Patent