BDBM682873 2-(2-chlorophenyl)-7- (6,7,8-trifluoroisoquinolin- 4-yl)-5,7- diazaspiro[3.4]octane- 6,8-dione::US20240208970, Compound 59::US20240208970, Compound 60
SMILES Fc1cc2c(cncc2c(F)c1F)N1C(=O)NC2(CC(C2)c2ccccc2Cl)C1=O
InChI Key InChIKey=CGNWWAJTBDKWKH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 682873
Affinity DataIC50: 6.60E+3nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
Affinity DataIC50: 1.37E+3nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
Affinity DataKd: 250nMAssay Description:The SPR experiments were performed using a Biacore S200 instrument and CM5 biosensor chips (Cytiva, Uppsala, Sweden) at 25 C. Streptavidin (Sigma) wa...More data for this Ligand-Target Pair
Affinity DataKd: 364nMAssay Description:The SPR experiments were performed using a Biacore S200 instrument and CM5 biosensor chips (Cytiva, Uppsala, Sweden) at 25 C. Streptavidin (Sigma) wa...More data for this Ligand-Target Pair