BDBM685207 US20240239788, Example 5

SMILES CN1CCCC1CCc1nc(N2CC3CCC(C2)N3C(=O)OC(C)(C)C)c2cc(Cl)c(c(F)c2n1)-c1cc(O)cc2ccccc12

InChI Key InChIKey=PRANFVGSKCOXET-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 685207   

TargetRAF proto-oncogene serine/threonine-protein kinase [50-132]/GTPase KRas [G12D](Human)
Merck Sharp & Dohme

US Patent

LigandBDBM685207(US20240239788, Example 5)Copy SMILESCopy InChI

Affinity DataIC50: 1.73E+4nMAssay Description:The RAF-Ras binding domain (RBD) protein interaction assay utilizes recombinant biotinylated KRAS protein containing a G12D mutation (SEQ ID NO: 1) a...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/30/2024
Entry Details
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