BDBM685220 US20240239788, Example 18b

SMILES CN(C)CC1(COc2nc(N3CC4CC(O)[C@@H](C3)N4)c3cc(Cl)c(c(F)c3n2)-c2cc(O)cc3ccccc23)CC1

InChI Key InChIKey=NFSXWVBZXHXQRC-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 685220   

TargetRAF proto-oncogene serine/threonine-protein kinase [50-132]/GTPase KRas [G12D](Human)
Merck Sharp & Dohme

US Patent

LigandBDBM685220(US20240239788, Example 18b)Copy SMILESCopy InChI

Affinity DataIC50: 2.68E+3nMAssay Description:The RAF-Ras binding domain (RBD) protein interaction assay utilizes recombinant biotinylated KRAS protein containing a G12D mutation (SEQ ID NO: 1) a...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/30/2024
Entry Details
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