BDBM685223 4-(2-((1-((dimethyl- amino)methyl)cyclo- propyl)methoxy)- 6,8-difluoro-4- ((1S,5R)-1-methyl-3,8- diazabicy- clo[3.2.1]octan- 3-yl)quinazolin-7- yl)naphthalen-2-ol::US20240239788, Example 21

SMILES CN(C)CC1(COc2nc(N3C[C@H]4CC[C@](C)(C3)N4)c3cc(F)c(c(F)c3n2)-c2cc(O)cc3ccccc23)CC1

InChI Key InChIKey=DNJMZBAPSYWRNK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 685223   

LigandPNGBDBM685223(US20240239788, Example 21 | 4-(2-((1-((dimethyl- a...)
Affinity DataIC50: 1.98E+3nMAssay Description:The RAF-Ras binding domain (RBD) protein interaction assay utilizes recombinant biotinylated KRAS protein containing a G12D mutation (SEQ ID NO: 1) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
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