BDBM686172 US20240245673, Example 324::rel-(R)-4-(2-methoxy-1-(thiazol-4-ylmethoxy)ethyl)-2-methyl-N-(1-(2-(1-methyl-1H-pyrazol-4-yl)quinolin-4-yl)cyclopropyl)benzamide, ENT-1

SMILES COC[C@@H](OCc1cscn1)c1ccc(C(=O)NC2(CC2)c2cc(nc3ccccc23)-c2cnn(C)c2)c(C)c1

InChI Key InChIKey=MSTHKDNKFSZPLA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 686172   

TargetReplicase polyprotein 1a(2019-nCoV)
Pfizer

US Patent
LigandPNGBDBM686172(US20240245673, Example 324 | rel-(R)-4-(2-methoxy-...)
Affinity DataIC50: 1nMAssay Description:The potency of compounds against the SARS-CoV-2 Papain like protease (PLpro) was measured using a synthetic profluorogenic substrate Z-RLRGG-AMC. Com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
Go to US Patent