BDBM686176 US20240245673, Example 328

SMILES Cc1cc(COCc2cscn2)ccc1C(=O)NC1(CC1)c1cc(nc2ccccc12)-c1cnn(CCS(C)(=O)=O)c1

InChI Key InChIKey=YGORPOURUXJURE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 686176   

TargetReplicase polyprotein 1a(2019-nCoV)
Pfizer

US Patent
LigandPNGBDBM686176(US20240245673, Example 328)
Affinity DataIC50: 1nMAssay Description:The potency of compounds against the SARS-CoV-2 Papain like protease (PLpro) was measured using a synthetic profluorogenic substrate Z-RLRGG-AMC. Com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
Go to US Patent