BDBM687764 US20240246972, Comparator 4

SMILES Cc1[nH]ncc1-c1ccc2cc([nH]c2n1)C(=O)NCc1ccccc1OC1COC1

InChI Key InChIKey=UBZNLGBMKJHEFB-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 687764   

TargetcAMP-dependent protein kinase catalytic subunit PRKX(Human)
Avicenna Biosciences, Inc.

US Patent
LigandPNGBDBM687764(US20240246972, Comparator 4)
Affinity DataIC50: 62nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Avicenna Biosciences, Inc.

US Patent
LigandPNGBDBM687764(US20240246972, Comparator 4)
Affinity DataIC50: 190nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Avicenna Biosciences, Inc.

US Patent
LigandPNGBDBM687764(US20240246972, Comparator 4)
Affinity DataIC50: 282nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Avicenna Biosciences, Inc.

US Patent
LigandPNGBDBM687764(US20240246972, Comparator 4)
Affinity DataIC50: 1.00E+3nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent