BDBM687767 Synthesis of N-(1-(3-(1-hydroxycyclopropyl)phenyl)cyclopropyl)-1-methyl-6-(1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide ::US20240246972, Compound 7

SMILES Cn1c(cc2ccc(nc12)-c1cn[nH]c1)C(=O)NC1(CC1)c1cccc(c1)C1(O)CC1

InChI Key InChIKey=MSROHJGQUMVBTJ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 687767   

TargetcAMP-dependent protein kinase catalytic subunit PRKX(Human)
Avicenna Biosciences, Inc.

US Patent
LigandPNGBDBM687767(US20240246972, Compound 7 | Synthesis of N-(1-(3-(...)
Affinity DataIC50: 28.2nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Avicenna Biosciences, Inc.

US Patent
LigandPNGBDBM687767(US20240246972, Compound 7 | Synthesis of N-(1-(3-(...)
Affinity DataIC50: 104nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Avicenna Biosciences, Inc.

US Patent
LigandPNGBDBM687767(US20240246972, Compound 7 | Synthesis of N-(1-(3-(...)
Affinity DataIC50: 357nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent