BDBM687771 Synthesis of N-{[2-(difluoromethyl)phenyl]methyl}-1-methyl-6-(1H-pyrazol-4-yl)pyrrolo[2,3-b]pyridine-2-carboxamide ::US20240246972, Compound 12

SMILES Cn1c(cc2ccc(nc12)-c1cn[nH]c1)C(=O)NCc1ccccc1C(F)F

InChI Key InChIKey=GUIBMJRAVIMUQK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 687771   

TargetRho-associated protein kinase 2(Human)
Avicenna Biosciences, Inc.

US Patent
LigandPNGBDBM687771(US20240246972, Compound 12 | Synthesis of N-{[2-(d...)
Affinity DataIC50: 8.30nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Avicenna Biosciences, Inc.

US Patent
LigandPNGBDBM687771(US20240246972, Compound 12 | Synthesis of N-{[2-(d...)
Affinity DataIC50: 47.1nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent