BDBM689244 5-[2-(2,2-difluoroethoxy)-4,4,4-trifluoro- butoxy]-3-methyl-N-(4-methyl-1,1-dioxo- thian-4-yl)imidazo[4,5-b]pyridine-2- carboxamide::US20240254114, Example 63b

SMILES Cn1c(nc2ccc(OC[C@@H](CC(F)(F)F)OCC(F)F)nc12)C(=O)NC1(C)CCS(=O)(=O)CC1

InChI Key InChIKey=ZKWKUFKZJINDSY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 689244   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM689244(US20240254114, Example 63b | 5-[2-(2,2-difluoroeth...)
Affinity DataIC50: 0.800nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
US Patent