BDBM690298 5-(1-(2-hydroxy-2-methylpropyl)-3,5-dimethyl-1H-pyrazol-4-yl)-N-(2-methyl-5-(5-methyl-2H-tetrazol-2-yl)phenyl)pyrazolo[1,5-a]pyridine-3-carboxamide::US20240262826, Compound 244

SMILES Cc1nnn(n1)-c1ccc(C)c(NC(=O)c2cnn3ccc(cc23)-c2c(C)nn(CC(C)(C)O)c2C)c1

InChI Key InChIKey=SIPFHHXGIXOXLY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 690298   

TargetMast/stem cell growth factor receptor Kit(Human)
Blueprint Medicines

US Patent
LigandPNGBDBM690298(5-(1-(2-hydroxy-2-methylpropyl)-3,5-dimethyl-1H-py...)
Affinity DataIC50: 0.400nMAssay Description:For the PathScan phospho c-kit (Tyr719) sandwich ELISA: M-07e cells were resuspended at 2×106 cells/mL in phenol red free, serum-free, GM-CSF-free Is...More data for this Ligand-Target Pair
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Date in BDB:
11/25/2024
Entry Details
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