BDBM690328 (R)-N-(2-chloro-5-(2-cyclopropyl-2H-tetrazol-5-yl)phenyl)-5-(3,5-dimethyl-1-((4-methylmorpholin-2-yl)methyl)-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carboxamide::US20240262826, Compound 274

SMILES CN1CCO[C@@H](Cn2nc(C)c(c2C)-c2ccn3ncc(C(=O)Nc4cc(ccc4Cl)-c4nnn(n4)C4CC4)c3c2)C1

InChI Key InChIKey=JPISQIHWQAZLBE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 690328   

TargetMast/stem cell growth factor receptor Kit(Human)
Blueprint Medicines

US Patent
LigandPNGBDBM690328((R)-N-(2-chloro-5-(2-cyclopropyl-2H-tetrazol-5-yl)...)
Affinity DataIC50: 0.600nMAssay Description:For the PathScan phospho c-kit (Tyr719) sandwich ELISA: M-07e cells were resuspended at 2×106 cells/mL in phenol red free, serum-free, GM-CSF-free Is...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2024
Entry Details
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