BDBM691545 US20240279215, Compound 6::oxazol-5-ylmethyl (R)- (4-((2-(pyridin-3- yl)pyrrolidin-1- yl)methyl)phenyl)carbamate

SMILES O=C(Nc1ccc(CN2CCC[C@@H]2c2cccnc2)cc1)OCc1cnco1

InChI Key InChIKey=TZGUJMKLEAYCHZ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 691545   

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandPNGBDBM691545(US20240279215, Compound 6 | oxazol-5-ylmethyl (R)-...)
Affinity DataEC50:  550nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
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Date in BDB:
11/26/2024
Entry Details
US Patent