BDBM691594 4-chlorobenzyl (4-((3,5- difluoro-N- methylisonicotinamido)meth- yl)phenyl)carbamate::US20240279215, Compound 55

SMILES CN(Cc1ccc(NC(=O)OCc2ccc(Cl)cc2)cc1)C(=O)c1c(F)cncc1F

InChI Key InChIKey=RGWYGUIQHVDLII-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 691594   

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandPNGBDBM691594(US20240279215, Compound 55 | 4-chlorobenzyl (4-((3...)
Affinity DataEC50:  1.82E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent