BDBM691637 US20240279215, Compound 98::methyl 4-(4-((((4- chlorobenzyl)oxy)car- bonyl)amino)benzyl)piperidine- 1-carboxylate

SMILES COC(=O)N1CCC(Cc2ccc(NC(=O)OCc3ccc(Cl)cc3)cc2)CC1

InChI Key InChIKey=XGKWHLYQMFIOMB-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 691637   

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandPNGBDBM691637(US20240279215, Compound 98 | methyl 4-(4-((((4- ch...)
Affinity DataEC50:  1.49E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent