BDBM691703 4-chlorobenzyl (S)-(4-(1-(6- (difluoromethyl)nicotinami- do)ethyl)phenyl)carbamate::US20240279215, Compound 164

SMILES C[C@H](NC(=O)c1ccc(nc1)C(F)F)c1ccc(NC(=O)OCc2ccc(Cl)cc2)cc1

InChI Key InChIKey=IJRPEYRMKISVLY-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 691703   

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandPNGBDBM691703(US20240279215, Compound 164 | 4-chlorobenzyl (S)-(...)
Affinity DataEC50:  1.60E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
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Date in BDB:
11/26/2024
Entry Details
US Patent