BDBM6918 3,4,5-trimethoxy-N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-indeno[1,2-c]pyrazol-5-yl]carbamoyl}amino)benzamide::acylsemicarbazide deriv. 3f

SMILES COc1ccc(cc1)-c1n[nH]c2-c3cccc(NC(=O)NNC(=O)c4cc(OC)c(OC)c(OC)c4)c3C(=O)c12

InChI Key InChIKey=TZSZKILLRMGQIE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 6918   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Dupont Pharmaceuticals

LigandPNGBDBM6918(3,4,5-trimethoxy-N-({[3-(4-methoxyphenyl)-4-oxo-2H...)
Affinity DataIC50: 7nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Dupont Pharmaceuticals

LigandPNGBDBM6918(3,4,5-trimethoxy-N-({[3-(4-methoxyphenyl)-4-oxo-2H...)
Affinity DataIC50: 20nMpH: 7.6 T: 2°CAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2005
Entry Details Article
PubMed