BDBM691898 US20240279215, Compound 359::US20240279215, Compound 360

SMILES CS(=O)(=O)N1CCC2(CC(C2)c2ccc(NC(=O)OCc3cnco3)cc2F)C1

InChI Key InChIKey=AUOKFXXTMKMHDW-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 691898   

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandPNGBDBM691898(US20240279215, Compound 360 | US20240279215, Compo...)
Affinity DataEC50:  2.33E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandPNGBDBM691898(US20240279215, Compound 360 | US20240279215, Compo...)
Affinity DataEC50:  3.50E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent