BDBM691915 US20240279215, Compound 376::oxazol-5-ylmethyl (R)- (4-(1- (dimethylcarbamoyl)piperidin-3- yl)phenyl)carbamate

SMILES CN(C)C(=O)N1CCC[C@@H](C1)c1ccc(NC(=O)OCc2cnco2)cc1

InChI Key InChIKey=LGKVMDADBLHZIK-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 691915   

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandPNGBDBM691915(US20240279215, Compound 376 | oxazol-5-ylmethyl (R...)
Affinity DataEC50:  2.02E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
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Date in BDB:
11/26/2024
Entry Details
US Patent