BDBM691929 US20240279215, Compound 390::oxazol-5-ylmethyl (4-((8- (piperidine-1-carbonyl)- 8-azabicyclo[3.2.1]octan-3- yl)methyl)phenyl)carbamate

SMILES O=C(Nc1ccc(CC2CC3CCC(C2)N3C(=O)N2CCCCC2)cc1)OCc1cnco1

InChI Key InChIKey=ZLGGQPIYIFPVKS-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 691929   

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandPNGBDBM691929(US20240279215, Compound 390 | oxazol-5-ylmethyl (4...)
Affinity DataEC50:  1.80E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
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Date in BDB:
11/26/2024
Entry Details
US Patent