BDBM691960 US20240279215, Compound 421::methyl 8-(4-(((oxazol-5- ylmethoxy)carbonyl)ami- no)benzyl)-3- azabicyclo[3.2.1]octane- 3-carboxylate

SMILES COC(=O)N1CC2CCC(C1)C2Cc1ccc(NC(=O)OCc2cnco2)cc1

InChI Key InChIKey=QZXOGUTUNWJOQP-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 691960   

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandPNGBDBM691960(US20240279215, Compound 421 | methyl 8-(4-(((oxazo...)
Affinity DataEC50:  2.33E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
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Date in BDB:
11/26/2024
Entry Details
US Patent