BDBM691973 US20240279215, Compound 434::oxazol-5-ylmethyl (4-((3- (methylsulfonyl)-3- azabicyclo[3.1.1]heptan-6- yl)methyl)phenyl)carbamate

SMILES CS(=O)(=O)N1CC2CC(C1)C2Cc1ccc(NC(=O)OCc2cnco2)cc1

InChI Key InChIKey=XGYVSUFVEXJXDP-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 691973   

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandPNGBDBM691973(US20240279215, Compound 434 | oxazol-5-ylmethyl (4...)
Affinity DataEC50:  2.11E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
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Date in BDB:
11/26/2024
Entry Details
US Patent