BDBM6927 acylsemicarbazide deriv. 3o::methoxy-N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-indeno[1,2-c]pyrazol-5-yl]carbamoyl}amino)formamide

SMILES COC(=O)NNC(=O)Nc1cccc2-c3[nH]nc(c3C(=O)c12)-c1ccc(OC)cc1

InChI Key InChIKey=CQRTXGVZEGGYSB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 6927   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Dupont Pharmaceuticals

LigandPNGBDBM6927(methoxy-N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-inden...)
Affinity DataIC50: 8nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Dupont Pharmaceuticals

LigandPNGBDBM6927(methoxy-N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-inden...)
Affinity DataIC50: 16nMpH: 7.6 T: 2°CAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2005
Entry Details Article
PubMed