BDBM693145 US12070513, Compound 6

SMILES CCCC[Sn](CCCC)(CCCC)c1cncc(c1)C(=O)NCCCCC(NC(=O)NC(CCC(=O)OCc1ccc(OC)cc1)C(=O)OCc1ccc(OC)cc1)C(=O)OCc1ccc(OC)cc1

InChI Key InChIKey=KPXBEUKROPHHDP-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 693145   

TargetN-acetylaspartylglutamate synthase A(Human)
Johns Hopkins Universty

US Patent
LigandPNGBDBM693145(US12070513, Compound 6)
Affinity DataKi:  0.194nMAssay Description:PSMA activity was also determined using a fluorescence-based assay according to a previously reported procedure. Briefly, lysates of LNCaP cell extra...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/6/2024
Entry Details
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TargetN-acetylaspartylglutamate synthase A(Human)
Johns Hopkins Universty

US Patent
LigandPNGBDBM693145(US12070513, Compound 6)
Affinity DataKi:  0.256nMAssay Description:NAAG hydrolysis was performed essentially as described previously (26)(27) Briefly, LNCaP cell extracts were prepared by sonication in NAALADase buff...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/6/2024
Entry Details
Go to US Patent