BDBM693146 US12070513, Compound 8

SMILES c1cc(ccc1C(=O)NCCCC[C@@H](C(=O)O)NC(=O)N[C@@H](CCC(=O)O)C(=O)O)I

InChI Key InChIKey=ROXRILBFJQYPNZ-UHFFFAOYSA-N

Data  2 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 693146   

TargetN-acetylaspartylglutamate synthase A(Human)
Johns Hopkins Universty

US Patent
LigandPNGBDBM693146(US12070513, Compound 8)
Affinity DataKi:  0.351nMAssay Description:NAAG hydrolysis was performed essentially as described previously (26)(27) Briefly, LNCaP cell extracts were prepared by sonication in NAALADase buff...More data for this Ligand-Target Pair
Ligand InfoPDBSimilars
In Depth
Date in BDB:
12/6/2024
Entry Details
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TargetN-acetylaspartylglutamate synthase A(Human)
Johns Hopkins Universty

US Patent
LigandPNGBDBM693146(US12070513, Compound 8)
Affinity DataKi:  0.557nMAssay Description:PSMA activity was also determined using a fluorescence-based assay according to a previously reported procedure. Briefly, lysates of LNCaP cell extra...More data for this Ligand-Target Pair
Ligand InfoPDBSimilars
In Depth
Date in BDB:
12/6/2024
Entry Details
Go to US Patent