BDBM693800 1-(5-(((1S,2S)-2-(3-(4,4- difluorocyclohexyl)azetidin-1- yl)cyclopentyl)oxy)-1-oxoisoindolin-2- yl)-3-azabicyclo[3.1.1]heptane-2,4- dione::US20240287037, Example 14

SMILES FC1(F)CCC(CC1)C1CN(C1)[C@H]1CCC[C@@H]1Oc1ccc2C(=O)N(Cc2c1)C12CC(C1)C(=O)NC2=O

InChI Key InChIKey=UGDYKJQJGCZAAV-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 693800   

TargetProtein cereblon(Human)
Plexium

US Patent
LigandPNGBDBM693800(1-(5-(((1S,2S)-2-(3-(4,4- difluorocyclohexyl)azeti...)
Affinity DataEC50: >1.00E+4nMAssay Description:Cereblon target engagement was monitored by Bioluminescence Resonance Energy Transfer (BRET) in transfected HEK-293T cells using the NanoBRET TE Intr...More data for this Ligand-Target Pair
Ligand InfoSimilars
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Date in BDB:
12/12/2024
Entry Details
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