BDBM693805 3-(5-(((1S,2S)-2-(3-(4- ethoxycyclohexyl)azetidin-1- yl)cyclohexyl)oxy)-1-oxoisoindolin-2- yl)piperidine-2,6-dione::US20240287037, Example 19

SMILES CCOC1CCC(CC1)C1CN(C1)[C@H]1CCCC[C@@H]1Oc1ccc2C(=O)N(Cc2c1)C1CCC(=O)NC1=O

InChI Key InChIKey=ZZEYWSILRYYFDR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 693805   

TargetProtein cereblon(Human)
Plexium

US Patent
LigandPNGBDBM693805(3-(5-(((1S,2S)-2-(3-(4- ethoxycyclohexyl)azetidin-...)
Affinity DataEC50:  1nMAssay Description:Cereblon target engagement was monitored by Bioluminescence Resonance Energy Transfer (BRET) in transfected HEK-293T cells using the NanoBRET TE Intr...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
Go to US Patent