BDBM693807 3-(5-(((1S,2S)-2-(3-(4- (difluoromethoxy)cyclohexyl)azetidin- 1-yl)cyclohexyl)oxy)-1-oxoisoindolin- 2-yl)piperidine-2,6-dione::US20240287037, Example 21

SMILES FC(F)OC1CCC(CC1)C1CN(C1)[C@H]1CCCC[C@@H]1Oc1ccc2C(=O)N(Cc2c1)C1CCC(=O)NC1=O

InChI Key InChIKey=KIWSRVUEUSJSNH-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 693807   

TargetProtein cereblon(Human)
Plexium

US Patent
LigandPNGBDBM693807(3-(5-(((1S,2S)-2-(3-(4- (difluoromethoxy)cyclohexy...)
Affinity DataEC50:  1nMAssay Description:Cereblon target engagement was monitored by Bioluminescence Resonance Energy Transfer (BRET) in transfected HEK-293T cells using the NanoBRET TE Intr...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
Go to US Patent