BDBM69620 (4-bromophenyl)(5-hydroxy-1-benzofuran-3-yl)methanone::(4-bromophenyl)-(5-hydroxy-1-benzofuran-3-yl)methanone::(4-bromophenyl)-(5-hydroxy-3-benzofuranyl)methanone::(4-bromophenyl)-(5-hydroxybenzofuran-3-yl)methanone::(4-bromophenyl)-(5-oxidanyl-1-benzofuran-3-yl)methanone::MLS001178337::SMR000476405::cid_900927

SMILES Oc1ccc2occ(C(=O)c3ccc(Br)cc3)c2c1

InChI Key InChIKey=ASNZTVAKQDBAGG-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 69620   

TargetSentrin-specific protease 8(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM69620(MLS001178337 | (4-bromophenyl)-(5-oxidanyl-1-benzo...)
Affinity DataIC50: 5.94E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2011
Entry Details
PCBioAssay
TargetSentrin-specific protease 6(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM69620(MLS001178337 | (4-bromophenyl)-(5-oxidanyl-1-benzo...)
Affinity DataIC50: 6.00E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2011
Entry Details
PCBioAssay
TargetGlycogen synthase kinase-3 beta(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM69620(MLS001178337 | (4-bromophenyl)-(5-oxidanyl-1-benzo...)
Affinity DataEC50:  1.54E+4nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details
PCBioAssay
TargetCaspase-3(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM69620(MLS001178337 | (4-bromophenyl)-(5-oxidanyl-1-benzo...)
Affinity DataIC50: 1.90E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2011
Entry Details
PCBioAssay
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM69620(MLS001178337 | (4-bromophenyl)-(5-oxidanyl-1-benzo...)
Affinity DataIC50: 2.40E+5nMAssay Description:Inhibition of N-terminal His6-tagged SIRT1 coding region (156-664) (unknown origin) expressed in Escherichia coli BL21(DE3) using 31.25 uM ac-RHKKac-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed