BDBM698903 US20240317759, Example 112

SMILES O=C1c2sc(-c3ccc(N4CC[C@@H](F)C4)nc3F)nc2CCN1c1ncccn1

InChI Key InChIKey=GZINDCNTOYGZDJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 698903   

TargetTAR DNA-binding protein 43(Human)
AC Immune

US Patent
LigandChemical structure of BindingDB Monomer ID 698903BDBM698903((S)-2-(2-fluoro-6-(3-fluoropyrrolidin-1-yl)pyridin...)
Affinity DataKi: >1.00E+3nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2026
Entry Details
US Patent