BDBM698937 1-(7-(8-bromo-3- hydroxynaphthalen-1-yl)-2-((1- ((dimethylamino)methyl)cyclo- propyl)methoxy)- 5,6,7,8-tetrahydropyrido[3,4- d]pyrimidin-4-yl)-1,4- diazepan-6-ol::US20240317759, Example 146

SMILES C#CC(=O)OC(=O)c1cc(OC)c(OC)c(OC)c1N

InChI Key InChIKey=PAIDKVOOXHZWQA-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 698937   

TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 698937BDBM698937(2-amino-3,4,5-trimethoxybenzoic propiolic anhydrid...)
Affinity DataIC50: 4.30nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent