BDBM698941 (R)-1-(2-(((R)-1-((dimethylamino)methyl)- 2,2-difluorocyclopropyl)methoxy)-7-(6- methyl-5-(trifluoromethyl)-1H-indazol-4-yl)- 5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4- yl)-3-methylpiperidin-3-ol::US20240317759, Example 150

SMILES FC1=C(COc2ccc3ccccc3c2)N=CC(c2nnc(C(F)F)o2)C1

InChI Key InChIKey=ANSHKUDPRXBYBR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 698941   

TargetHistone deacetylase 6(Human)
Eikonizo Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 698941BDBM698941(2-(Difluoromethyl)-5-(5-fluoro-6-((naphthalen-2-yl...)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2026
Entry Details
US Patent