BDBM700233 N-[Dimethyl(oxo)-λ6-sulfanylidene]-5-methyl-2-[[4-[1-methyl-4-(4-pyridyl)pyrazol-3-yl]phenoxy]methyl]quinoline-3-carboxamide::US20240336591, Example 7

SMILES Cc1cccc2nc(COc3ccc(cc3)-c3nn(C)cc3-c3ccncc3)c(cc12)C(=O)N=S(C)(C)=O

InChI Key InChIKey=OTGPXNFTBKOICG-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 700233   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform 2(Human)
Benevolentai Cambridge

US Patent

LigandBDBM700233(N-[Dimethyl(oxo)-λ6-sulfanylidene]-5-methyl-2...)Copy SMILESCopy InChI

Affinity DataIC50: 0.224nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
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Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/10/2025
Entry Details
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