BDBM700264 N-[Dimethyl(oxo)-λ6-sulfanylidene]-7-fluoro-2-[[4-[l-methyl-4-(4-pyridyl)pyrazol-3-yl]phenoxy]methyl]quinoline-3-carboxamide::US20240336591, Example 21

SMILES Cn1cc(c(n1)-c1ccc(OCc2nc3cc(F)ccc3cc2C(=O)N=S(C)(C)=O)cc1)-c1ccncc1

InChI Key InChIKey=IKYFZDXXUGHOPQ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 700264   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform 2(Human)
Benevolentai Cambridge

US Patent

LigandBDBM700264(N-[Dimethyl(oxo)-λ6-sulfanylidene]-7-fluoro-2...)Copy SMILESCopy InChI

Affinity DataIC50: 4.79nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
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Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/10/2025
Entry Details
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