BDBM700269 N-[Dimethyl(oxo)-lambda6- sulfanylidene]-5- fluoro-2-[[4-[1- methyl-4-(4- pyridyl)pyrazol-3- yl]phenoxy]methyl] quinoline-3- carboxamide::US20240336591, Example 23

SMILES Cn1cc(c(n1)-c1ccc(OCc2nc3cccc(F)c3cc2C(=O)N=S(C)(C)=O)cc1)-c1ccncc1

InChI Key InChIKey=VCNCZEJRLGKNPE-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 700269   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform 2(Human)
Benevolentai Cambridge

US Patent

LigandBDBM700269(N-[Dimethyl(oxo)-lambda6- sulfanylidene]-5- fluoro...)Copy SMILESCopy InChI

Affinity DataIC50: 0.257nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/10/2025
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL