BDBM700281 2-[[4-[1-Cyclopropyl- 4-(4-pyridyl)pyrazol- 3- yl]phenoxy]methyl]- N-[dimethyl(oxo)-lambda6- sulfanylidene] quinoline-4- carboxamide::US20240336591, Example 28

SMILES CS(C)(=O)=NC(=O)c1cc(COc2ccc(cc2)-c2nn(cc2-c2ccncc2)C2CC2)nc2ccccc12

InChI Key InChIKey=YVJMCAOQNVFCSR-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 700281   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform 2(Human)
Benevolentai Cambridge

US Patent

LigandBDBM700281(2-[[4-[1-Cyclopropyl- 4-(4-pyridyl)pyrazol- 3- yl]...)Copy SMILESCopy InChI

Affinity DataIC50: 0.380nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/10/2025
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL