BDBM701120 US20240343747, Example B2

SMILES CCC(=O)c1cnc(NC(=O)C2CC2)cc1Nc1cccc(-c2cc(P(C)(C)=O)n(C)n2)c1OC

InChI Key InChIKey=KCTPWUWVGQXNIC-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 701120   

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM701120(US20240343747, Example B2)
Affinity DataKd:  0.0430nMAssay Description:The lysates were centrifuged and filtered to remove cell debris. The remaining kinases were produced in HEK-293 cells and subsequently tagged with DN...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM701120(US20240343747, Example B2)
Affinity DataKd: >3.00E+4nMAssay Description:The lysates were centrifuged and filtered to remove cell debris. The remaining kinases were produced in HEK-293 cells and subsequently tagged with DN...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
Go to US Patent