BDBM701281 US12123010, Compound Uracilpyridine 10

SMILES Cn1c(C(F)(F)F)cc(=O)n(-c2nc(Oc3ccccc3OCC(=O)NS(C)(=O)=O)c(Cl)cc2F)c1=O

InChI Key InChIKey=JTFKNYMZVNFMSV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 701281   

TargetProtoporphyrinogen oxidase [L397E,F420M](Rough-fruited waterhemp)
Basf

US Patent
LigandPNGBDBM701281(US12123010, Compound Uracilpyridine 10)
Affinity DataIC50: 6.51E+3nMAssay Description:Proto is purchased from Sigma-Aldrich (Milwaukee, WI). Protogen is prepared according to Jacobs and Jacobs (N. J. Jacobs, J. M. Jacobs, Assay for enz...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/25/2025
Entry Details
Go to US Patent

TargetProtoporphyrinogen oxidase [R128A,F420M](Rough-fruited waterhemp)
Basf

US Patent
LigandPNGBDBM701281(US12123010, Compound Uracilpyridine 10)
Affinity DataIC50: 1.67E+3nMAssay Description:Proto is purchased from Sigma-Aldrich (Milwaukee, WI). Protogen is prepared according to Jacobs and Jacobs (N. J. Jacobs, J. M. Jacobs, Assay for enz...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/25/2025
Entry Details
Go to US Patent

TargetProtoporphyrinogen oxidase(Rough-fruited waterhemp)
Basf

US Patent
LigandPNGBDBM701281(US12123010, Compound Uracilpyridine 10)
Affinity DataIC50: 0.212nMAssay Description:Proto is purchased from Sigma-Aldrich (Milwaukee, WI). Protogen is prepared according to Jacobs and Jacobs (N. J. Jacobs, J. M. Jacobs, Assay for enz...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/25/2025
Entry Details
Go to US Patent