BDBM701461 US20240352000, Example 7

SMILES COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(C)c(Nc2cccc3c2N(S(C)(=O)=O)CC3)n1

InChI Key InChIKey=VDUMLKHYKWSAFL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 701461   

TargetEpidermal growth factor receptor [1-18,20-1210,T790M](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM701461(US20240352000, Example 7)
Affinity DataIC50: 1nMAssay Description:An experiment to measure the activity of the compounds of the present invention against EGFR mutant enzymes was performed as follows using the HTRF s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2025
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM701461(US20240352000, Example 7)
Affinity DataIC50: 1nMAssay Description:An experiment to measure the activity of the compounds of the present invention against EGFR mutant enzymes was performed as follows using the HTRF s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2025
Entry Details
Go to US Patent