BDBM7056 (4R,5S,6S,7R)-1,3-dibenzyl-4,7-bis({[4-(dimethylamino)phenyl]methyl})-5,6-dihydroxy-1,3-diazepan-2-one::(4R,5S,6S,7R)-Hexahydro-5,6-dihydroxy-1,3-bis-(phenylmethyl)-4,7-bis[[4-(N,N-dimethylamino)phenyl]methyl]-2H-1,3-diazapin-2-one::Substituted Cyclic Urea 44

SMILES CN(C)c1ccc(C[C@@H]2[C@H](O)[C@@H](O)[C@@H](Cc3ccc(cc3)N(C)C)N(Cc3ccccc3)C(=O)N2Cc2ccccc2)cc1

InChI Key InChIKey=NRADIIAUVVXPHY-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 7056   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandPNGBDBM7056((4R,5S,6S,7R)-Hexahydro-5,6-dihydroxy-1,3-bis-(phe...)
Affinity DataKi:  46nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2006
Entry Details Article
PubMed