BDBM708410 methyl 3-amino-6-((1-(2-(2,4- difluorophenyl)-2-hydroxy-3- (1H-1,2,4-triazol-1- yl)propyl)piperidin-4- yl)carbamoyl)-2-oxo-1-(4- phenyl-3,4-dihydro-2H- benzo[b][1,4]oxazin-6-yl)-1,2- dihydrothieno[2,3-b]pyrazine- 7-carboxylate::US20240424113, Compound I-55

SMILES COC(=O)c1c(C(=O)NC2CCN(CC(O)(Cn3cncn3)c3ccc(F)cc3F)CC2)sc2nc(N)c(=O)n(-c3ccc4c(c3)N(c3ccccc3)CCO4)c12

InChI Key InChIKey=UDDURITZQHAXLC-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 708410   

TargetHeat shock protein 90(Neosartorya fumigata)
Bright Angel Therapeutics

US Patent
LigandPNGBDBM708410(methyl 3-amino-6-((1-(2-(2,4- difluorophenyl)-2-hy...)
Affinity DataKd:  314nMAssay Description:Surface Plasmon Resonance (SPR) Experiments. SPR experiments were performed on a Biacore S200 instrument at 25° C. Biotinylated Hsp90 Nuclear Binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent

TargetHeat shock protein 90 homolog(Yeast)
Bright Angel Therapeutics

US Patent
LigandPNGBDBM708410(methyl 3-amino-6-((1-(2-(2,4- difluorophenyl)-2-hy...)
Affinity DataKd:  318nMAssay Description:Surface Plasmon Resonance (SPR) Experiments. SPR experiments were performed on a Biacore S200 instrument at 25° C. Biotinylated Hsp90 Nuclear Binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent