BDBM708418 3-amino-6-((4-(2-(2,4- difluorophenyl)-2-hydroxy-3- (1H-1,2,4-triazol-1- yl)propyl)piperazin-1- yl)methyl)-1-(4-phenyl-3,4- dihydro-2H- benzo[b][1,4]oxazin-6- yl)thieno[2,3-b]pyrazin-2(1H)- one::US20240424113, Compound I-68

SMILES Nc1nc2sc(CN3CCN(CC(O)(Cn4cncn4)c4ccc(F)cc4F)CC3)cc2n(-c2ccc3c(c2)N(c2ccccc2)CCO3)c1=O

InChI Key InChIKey=DDOZIPIDVCULMB-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 708418   

TargetHeat shock protein 90 homolog(Yeast)
Bright Angel Therapeutics

US Patent
LigandPNGBDBM708418(3-amino-6-((4-(2-(2,4- difluorophenyl)-2-hydroxy-3...)
Affinity DataKd:  417nMAssay Description:Surface Plasmon Resonance (SPR) Experiments. SPR experiments were performed on a Biacore S200 instrument at 25° C. Biotinylated Hsp90 Nuclear Binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent

TargetHeat shock protein 90(Neosartorya fumigata)
Bright Angel Therapeutics

US Patent
LigandPNGBDBM708418(3-amino-6-((4-(2-(2,4- difluorophenyl)-2-hydroxy-3...)
Affinity DataKd:  545nMAssay Description:Surface Plasmon Resonance (SPR) Experiments. SPR experiments were performed on a Biacore S200 instrument at 25° C. Biotinylated Hsp90 Nuclear Binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent