BDBM70894 2-furfuryl-[2-(m-toluidino)quinazolin-4-yl]amine;hydrochloride::4-N-(furan-2-ylmethyl)-2-N-(3-methylphenyl)quinazoline-2,4-diamine;hydrochloride::MLS000662793::N4-(2-furanylmethyl)-N2-(3-methylphenyl)quinazoline-2,4-diamine;hydrochloride::N4-(furan-2-ylmethyl)-N2-(3-methylphenyl)quinazoline-2,4-diamine;hydrochloride::N~4~-(2-furylmethyl)-N~2~-(3-methylphenyl)-2,4-quinazolinediamine hydrochloride::SMR000270242::cid_2910633

SMILES Cc1cccc(Nc2nc(NCc3ccco3)c3ccccc3n2)c1

InChI Key InChIKey=DPRZKNDPFKQQOC-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 70894   

TargetCOUP transcription factor 2(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM70894(cid_2910633 | SMR000270242 | N4-(furan-2-ylmethyl)...)
Affinity DataIC50: 8.50E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2013
Entry Details
PCBioAssay
TargetSon of sevenless homolog 1(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM70894(cid_2910633 | SMR000270242 | N4-(furan-2-ylmethyl)...)
Affinity DataEC50:  1.64E+4nMAssay Description:Activation of SOS1 in human HeLa cells assessed as increase in RAS-GTP levels after 30 mins by pull-down assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetTegument protein VP16(HHV-1)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM70894(cid_2910633 | SMR000270242 | N4-(furan-2-ylmethyl)...)
Affinity DataIC50: 5.30E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2014
Entry Details
PCBioAssay