BDBM710319 7-((5'S,7a'R)-5'-(5- fluoropyridin-3-yl)-3'- oxotetrahydro-3'H- spiro[piperidine-4,2'- pyrrolo[2,1-b]oxazol]- 1-yl)pyrazolo[1,5- a]pyridine-4- carbonitrile::US12180226, Example 14.3

SMILES N#Cc1ccc(N2CCC3(CC2)O[C@@H]2CC[C@@H](c4cncc(F)c4)N2C3=O)n2nccc12

InChI Key InChIKey=LVDYCMFQQQABRH-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 710319   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 710319BDBM710319(7-((5'S,7a'R)-5'-(5- fluoropyridin-3-yl)-3'- oxote...)
Affinity DataEC50: <2.50E+4nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution; top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
US Patent